Dieser Anti-ARID1A Antikörper ist ein Kaninchen Monoklonal Antikörper zur Detektion von ARID1A in WB, IHC, ICC, IP und FACS. Geeignet für Human und Maus.
Produktnummer ABIN7795678
Kurzübersicht für Rekombinanter ARID1A Antikörper (AA 750-800) (ABIN7795678)
The SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin (SMARC), also called BRG1-associated factors (BAFs), have been identified as components of the human SWI/SNF-like chromatin-remodeling protein complexes. SWI/SNF complexes possess ATPase and DNA helicase activity that promotes transcriptional activation of genes normally repressed by chromatin structure. ARID1A/BAF250 is a noncatalytic subunit that is a member of the ARID (AT-rich interactive domain-containing protein) family of DNA binding proteins. ARID1A/BAF250 has been shown to play a role in the tumor suppressor activity of the SWI/SNF complexes. ARID1A/BAF250 is required for differentiation-associated cell cycle arrest.